The intermediates are a very important type of fine chemical products. Essentially, they are a kind of "semi-finished product", an intermediate product in the production of certain products. For instance, to produce a certain product, production can start from the intermediates to save costs. These intermediates are widely used in the synthesis of pharmaceuticals, pesticides, coatings, dyes, and fragrances. In the pharmaceutical field, intermediates are a crucial link in the industry's supply chain. They are chemical raw materials or products used in the synthesis process of pharmaceuticals, essentially serving as substances for producing active pharmaceutical ingredients. Similarly, pesticide intermediates are also intermediary mediums that combine two or more agricultural raw materials.
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Pesticides refer to substances or a mixture and its preparations used to prevent, eliminate, or control harmful organisms to agriculture and forestry such as diseases, pests, weeds, and other harmful organisms, and purposefully regulate the growth of plants and insects, whether they are chemically synthesized or derived from biological or other natural substances. The pesticide industry is at the end of the chemical industry chain and belongs to the fine chemical industry. The upstream of the pesticide industry chain includes the petroleum/chemical industries, which provide raw materials for the pesticide industry. The midstream industry mainly consists of intermediates, raw drugs, and formulations, while the downstream includes agricultural applications and non-agricultural applications. The pesticide industry is highly dependent on technology, with significant investments in research and development, long cycles, high risks, and low success rates. In the context of the global population growth and the reduction of arable land, the extensive use of pesticides to increase yield per unit area is an important solution to food problems.
Different pesticides require different intermediates during production. Products processed from agricultural raw materials are also intermediate mediums that combine two or more substances. In pesticides, they can be understood as synergists, also known as organic intermediates. Initially, this referred to intermediate products produced during the synthesis of chemical products such as fragrances, dyes, resins, pharmaceuticals, plasticizers, and rubber accelerators using coal tar or petroleum products as raw materials.
The synthesis of intermediates is generally carried out in a reactor, and the generated intermediates need to be separated and purified, usually achieved using extraction technology. Chloroform extraction of pesticide intermediates is a common operation unit in chemical enterprises. Traditional extraction processes generally use distillation columns, a method that is complex, has low extraction efficiency, and is energy-consuming. Therefore, with the deeper social division of labor and progress in production technology, most enterprises have begun to carry out technical reforms and adopt more efficient processes for operations. Among these, solvent extraction has become the main operation unit in the extraction section of the chemical field. Solvent extraction involves selecting a suitable extractant, mixing the raw solution with the extractant, transferring the organic phase in the raw solution to the extractant, and then separating the two phases to extract the organic phase. This method is simple to operate, has high extraction efficiency, uses cheap and readily available extractants, and allows the extractant to be recycled, effectively saving overall input costs.
According to organic intermediates wholesale suppliers, producing pesticide intermediates involves multiple challenges requiring expertise and precision. One major challenge is ensuring the purity of the intermediates. Any impurities can impact the efficacy of the final pesticide product and potentially cause unexpected harm to crops or the environment.
Reformchem addresses these challenges through strict quality control measures and advanced manufacturing technologies. By adhering to rigorous regulatory standards and implementing comprehensive testing protocols, Reformchem ensures that its intermediates possess the highest purity and consistency. Additionally, by staying abreast of global regulatory changes, Reformchem is able to adapt and ensure compliance, further solidifying its reputation as a leader in the field.
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March 21, . Pesticide intermediates are fine chemicals. Pesticide intermediates are produced by processing agricultural raw materials. They are intermediate media that combine two or more substances together. In pesticides, they can be understood as synergists and intermediate materials for pesticide production. With the development of new pesticides in China, the development of some special intermediates is fast, such as fluorine-containing, cyano-containing and heterocycle containing intermediates. Among them, pyrethroid pesticide intermediates, such as pyrethroid, dichloropyrethric acid, butyric acid, ether aldehyde and allyl alcohol ketone, are more prominent. These intermediates are mainly produced in Shanghai, Zhejiang, Jiangsu and Shandong.
China is the main producer and supplier of pesticide fine chemical intermediates in the world, and its development prospect is very broad. Among them, 1,2,4-trichlorobenzene, o-cresol, catechol and nonylphenol are the most important pesticide intermediates. 1,2,4-trichlorobenzene is mainly used in the synthesis of pesticides such as dicamba, dicofol, sodium pentachlorophenol, pentachlorophenol, etc.; o-cresol is mainly used in the synthesis of high-efficiency herbicides; catechol is an important intermediate of carbofuran, propoxur and acetochlor; nonylphenol is a multi-purpose non-ionic surfactant, which is widely used in pesticide emulsifier; M-cresol is mainly used in the synthesis of pesticides and insecticides.
In recent years, due to the development and application of its downstream products at home and abroad, there is a strong demand for high purity 1,2,4-trichlorobenzene in the international market. In addition, due to the prohibition and restriction of lindane use, the traditional raw materials of Trichlorobenzene are decreasing day by day in developed countries and regions abroad, and the production of organochlorine products is also gradually reduced, which also leads to the shortage of global supply of Trichlorobenzene, especially high-purity 1,2,4-trichlorobenzene. These factors provide a good opportunity for the production and development of 1,2,4-trichlorobenzene in China. The new carbamate insecticides produced by catechol, such as carbofuran, propoxur and acetamivir, are recommended by the World Health Organization as excellent varieties of household and warehouse pest control pesticides due to their low toxicity and good effect, and the market demand will gradually increase. Nonylphenol is the largest product of alkylphenol. It has good functions of decontamination, wetting and penetration, dispersion, solubilization and emulsification. It is widely used in pesticide emulsifier and is the most important intermediate in petrochemical industry and organic synthesis industry. However, the market demand for m-cresol has basically maintained an average annual growth rate of 8% - 10%, with a stable development rate. In addition, because fine chemical industry has the advantages of functionalization, high performance, special flowers and high added value, it is a low-carbon, environment-friendly process, and a general path to achieve the national energy-saving and emission reduction goals and develop low-carbon economy, so the state attaches great importance to it. It is also very beneficial to the development of fine chemical pesticide intermediate industry.
The upstream of pesticide intermediates are inorganic raw materials such as yellow phosphorus and liquid chlorine, and basic organic raw materials such as methanol and triphenyl, which are used in agriculture, forestry and animal husbandry production and health field after being made into pesticide technical medicines. Agricultural intermediates are located in the middle of the industrial chain, belonging to the fine chemical industry, which is highly dependent on technology, with large R & D investment, long cycle, high risk and low success rate.
Therefore, China's fine chemical pesticide intermediates industry has a very good development prospect under the dual favorable influence of market demand and government's encouraging development.